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Does Antabuse reduce cravings? Antabuse (disulfiram) can help decrease cravings for alcohol, albeit indirectly. Still, Antabuse's effects on craving have not been specifically evaluated or evidenced in research. However, disulfiram has been shown to interfere with the metabolism of dopamine, potentially influencing the development of craving.
Do I need a prescription for disulfiram? Disulfiram is a prescription medication and should only be taken under the supervision of a physician. Disulfiram should only be taken after the patient has gone through the initial period of withdrawal and detox, has completely abstinence from alcohol for at least 12 hours, and has a blood alcohol level of zero.
When can you drink after disulfiram? People starting disulfiram should not take their first dose of the medication until at least 12 hours after their last drink of alcohol. Taking disulfiram too soon after drinking causes a reaction that can lead to severe illness.
How long does Antabuse last? The half life of Antabuse is 60-120 hours and up to 20% of a single dose may remain in the body for a week or more. Antabuse starts to affect ethanol metabolism within 1-2 hours after administration. Following a single dose of the medication, the body may react to any amount of alcohol for up to 14 days.
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