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Other drugs that have significant limitations of use because of their hepatotoxic effects are felbamate (Felbatol), an antiepileptic used for complex partial seizures; zileuton (Zyflo), indicated for asthma; tolcapone (Tasmar), used for Parkinson disease; trovafloxacin (Trovan), an antibiotic; benoxaprofen, an NSAID; and tienilic acid, a diuretic.
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When considered individually, most of the laboratory tests included in the SLICC classification criteria provide high specificity (86% to 99%) and low to medium sensitivity for SLE (7% to 59%).
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