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These tables show (1) the proportion of patients experiencing treatment failure, (2) the proportion of patients who experienced biopsy-proven acute rejection on treatment, and (3) early termination, for any reason other than graft loss or death, without a prior biopsy-proven acute rejection episode.

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The dose normalized AUC in de novo liver transplant patients administered Cyclosporine Oral Solution USP MODIFIED 28 days after transplantation was 50% greater and C max was 90% greater than in those patients administered Sandimmune (Cyclosporine Oral Solution USP).

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Orally administered radiolabeled mycophenolate mofetil resulted in complete recovery of the administered dose, with 93% of the administered dose recovered in the urine and 6% recovered in feces.

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While gleaning information from various patients who had been prescribed a rather extended dose of cyclosporine, the more common cyclosporine side effects were found to be trembling of hands, headache, oily skin, increases hair growth, kidney problems, fever, vomiting, high blood pressure, increased urination habit, high blood pressure, seizures, leg cramps, enlarged gums, changes in blood chemistry, gum bleeding and nausea.

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