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In placebo-controlled clinical trials with the immediate-release formulation of paroxetine, patients exhibited abnormal values on liver function tests at no greater rate than that seen in placebo-treated patients.

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Coadministration of the CYP 3A4 inducer phenytoin resulted in a 5-fold increase in the clearance of quetiapine; however, coadministration of cimetidine did not significantly affect its steady-state concentration.

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Bobo WV, Epstein RA, Shelton RC (2010) Olanzapine monotherapy for acute depression in patients with bipolar I or II disorder: results of an 8-week open label trial.

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Dell'Osso and colleagues (2005) noted that in addition to pharmacological, behavioral, and neurosurgical interventions, different brain stimulation methods such as transcranial magnetic stimulation, deep brain stimulation, as well as ECT have been examined in treatment-resistant patients with OCD.

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Take Sulpiride until your doctor decides to stop the therapy.

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See Specific Drugs under Interactions and see also Advice to Patients.

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Hyperprolactinemia has been documented in the majority of patients treated with irradiation because of CNS malignancies ().

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Inform your doctor immediately if you notice the following symptoms: anxiety, abrupt changes in mood or behavior, trouble sleeping, panic attacks, or if you are too irritable, impulsive, agitated, aggressive, hostile, restless, more depressed, hyperactive, or have thoughts about suicide or hurting yourself.

Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking.

May cause a decrease in serum uric acid.

This is because anti-anxiety medications tend to metabolize slowly and build up in the body.

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Clonidine or guanfacine may be appropriate as a first agent in many patients.

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The prevalence of OCD in every culture studied is at least 2% of the population, and the majority of those have obsessions, or bad thoughts, only; this results in a conservative estimate of more than 2 million sufferers in the United States alone (as of 2000).

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